eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | tuberous sclerosis |
| Symptom | C0037763|spasms |
| Sentences | 10 |
| PubMedID- 23796861 | Epileptic spasms in tuberous sclerosis complex. |
| PubMedID- 23399947 | Vigabatrin (vgb) has been shown to be particularly effective in the treatment of infantile spasms for those with tuberous sclerosis complex (tsc). |
| PubMedID- 21077355 | Vigabatrin (vgb) is one of the most effective anti-epileptic drugs for tonic spasms, those accompanied with tuberous sclerosis complex (tsc), but is not available in japan. |
| PubMedID- 21127692 | Chiron et al reported on a prospective trial comparing vigabatrin with hydrocortisone as initial treatment for infantile spasms attributable to tuberous sclerosis. |
| PubMedID- 23400943 | Some efficacy trends were identified, including frequent successes with valproic acid with clonazepam for epilepsy with angelman syndrome; valproic acid, stiripentol, and clobazam (triple combination therapy) for epilepsy with dravet syndrome; and vigabatrin for infantile spasms associated with tuberous sclerosis complex. |
| PubMedID- 24382900 | Vigabatrin is the drug of choice for infantile spasms associated with tuberous sclerosis. |
| PubMedID- 24910743 | This result is in agreement with hancock et al, who reported that vigabatrin ceased infantile spasms in 54% of infants without tuberous sclerosis compared with 95% of infants with tuberous sclerosis. |
| PubMedID- 24808722 | Vigabatrin often has marked efficacy in focal epilepsy or infantile spasms associated with tuberous sclerosis complex. |
| PubMedID- 25143766 | Vigabatrin has been used in the treatment of is in europe since 1990, and seems highly effective in spasms due to tuberous sclerosis. |
| PubMedID- 22180964 | Efficacy of topiramate for relapsed epileptic spasms with tuberous sclerosis: report of three cases. |
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